Rizzoli and Isles The Boston Bloodline 2026 Starring Angie Harmon, Sasha Alexander, Jordan Bridges, and Lorraine Bracco
The unstoppable duo of the badge and the scalpel are officially back in business. In the highly anticipated return, Rizzoli and Isles The Boston Bloodline, Jane Rizzoli, played by Angie Harmon, has spent the last several years rising through the ranks at the FBI. However, a single chilling phone call from the Boston Police Department pulls her racing back to her roots. A new serial killer, operating with terrifying surgical precision, is systematically targeting families connected to high profile cold cases. Even more disturbing is that all signs suggest this is not random; it is a calculated vendetta specifically aimed at destroying the Rizzoli name.
Angie Harmon returns to the screen with her signature gravelly grit and fearless attitude, looking sharper and more commanding than ever as she navigates the dangerous and familiar streets of Boston. Beside her stands Maura Isles, portrayed by Sasha Alexander, who brings her flawless intellect and high fashion clinical elegance back to the morgue. This time, Maura is armed with cutting edge forensic AI to track a ghost like killer who is careful to leave absolutely no DNA behind. Their legendary chemistry, a unique blend of deep sisterly love and hilarious, rapid fire bickering, remains the absolute heart of the story. It proves that while their individual lives have evolved, their bond remains completely unbreakable. Jordan Bridges reprises his role as Frankie Rizzoli Jr, who has matured into a seasoned veteran detective, while the family matriarch Angela, played by Lorraine Bracco, provides the much needed Mama Rizzoli wisdom and warm Italian comfort that keeps the team grounded.
The investigation unfolds as a high stakes race against time, winding through Bostons most iconic historic landmarks and its darkest, hidden alleyways. As the killer closes in on the people they love most, Jane and Maura are forced to combine old school street smarts with advanced scientific genius. They must work together to solve a complex puzzle that has been decades in the making, uncovering secrets that threaten to tear their world apart.
Sleek, emotional, and packed with the witty banter that defined a generation of viewers, The Boston Bloodline is a stylish and welcome return for televisions favorite crime fighting duo. It serves as a pulse pounding reminder that when it comes to protecting her family, Jane Rizzoli does not just follow the law, she defines it.
